Ackr3 - atypical chemokine receptor 3 Gene

Rattus norvegicus

Also known as Rdc1; Cxcr7; Cmkor1

Gene ID: 84348 | Gene type: protein coding

About Ackr3

Primary_assembly 9: 90,799,686-90,811,237 forward strand.mRatBN7.2:CM026982.1

This gene has 6 transcripts (splice variants), 252 orthologues, 24 paralogues and is associated with 12 phenotypes. Biased expression in Heart (RPKM 129.4), Lung (RPKM 118.2) and 9 other tissues.

Summary

Predicted to enable chemokine binding activity; Chemokine Receptor activity; and scavenger receptor activity. Involved in positive regulation of mesenchymal stem cell migration. Located in cytoplasm; nucleus; and plasma membrane. Orthologous to human ACKR3 (atypical Chemokine Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ackr3 Products(1)

mRNA	Protein	Name
NM_053352.2	NP_445804.1	atypical chemokine receptor 3

Ackr3 Protein Structure

7tmA_ACKR3_CXCR7

0
100
200
300
362 a.a.

Protein Preferred Names

Protein Names

atypical chemokine receptor 3

C-X-C chemokine receptor type 7	CXC-R7
CXCR-7	G-protein coupled receptor RDC1 homolog
RDC-1	chemokine (C-X-C motif) receptor 7
chemokine orphan receptor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-123813	CCX-777	Agonist	98.73%	Unkown
HY-161414	trans-VUF25471		/	Unkown
HY-D2201	Fluorescent ACKR3 antagonist 1		/	Unkown
HY-RS00162	ACKR3 Human Pre-designed siRNA Set A		/	Unkown
HY-RS00163	Ackr3 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS00164	Ackr3 Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ackr3	NCBI	NCBI:57007

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