1. Gene
  2. NAPA - NSF attachment protein alpha Gene

NAPA - NSF attachment protein alpha Gene

Homo sapiens

Also known as SNAPA

Gene ID: 8775 | Gene type: protein coding

About NAPA

Cytogenetic location: 19q13.32-q13.33 Genomic coordinates (GRCh38): 19:47,484,530-47,515,063 (from NCBI)

This gene has 22 transcripts (splice variants), 222 orthologues and 2 paralogues. Ubiquitous expression in prostate (RPKM 53.4), adrenal (RPKM 52.5) and 25 other tissues.

Summary

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]

NAPA Products(1)

mRNA Protein Name
NM_003827.4 NP_003818.2 alpha-soluble NSF attachment protein

NAPA Protein Structure

SNAP

SNAP: Soluble NSF attachment protein, SNAP (9 - 288)

  • 0
  • 100
  • 200
  • 295 a.a.
Protein Preferred Names Protein Names

alpha-soluble NSF attachment protein

N-ethylmaleimide-sensitive factor attachment protein, alpha

Recombinant NAPA Proteins

Cat. No. Product Name Accession Purity
HY-P71326 SNAP-alpha Protein, Human (His) P54920 (M1-R295) ≥95%

Related Diseases

Diseases Alias
Tetanus

Lockjaw

Clostridial Tetanus

Infection Due To Clostridium Tetani

Lock-Jaw

Polyomavirus-Associated Nephropathy

Polyomavirus Associated Nephropathy

Pvan

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus NAPA VGNC VGNC:68414
Rattus norvegicus NAPA RGD RGD:620855
Macaca mulatta NAPA VGNC VGNC:75131
Canis familiaris NAPA VGNC VGNC:43619
Mus musculus NAPA MGD MGI:104563
Bos taurus NAPA VGNC VGNC:31881
Others NAPA NCBI