SAMD1 - sterile alpha motif domain containing 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 90378

About SAMD1

This gene has 3 transcripts (splice variants), 1 gene allele, 193 orthologues and 18 paralogues. Ubiquitous expression in colon (RPKM 8.2), brain (RPKM 8.2) and 25 other tissues.

Summary

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SAMD1 Products (1)

mRNA Protein Name
NM_138352.3 NP_612361.1 sterile alpha motif domain-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
33980486 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33980486 GOA
Biological Process GO Annotation Evidence References Source
involved in protein homooligomerization IDA
IDA: Inferred from direct assay
33980486 GOA
involved in regulation of DNA methylation-dependent heterochromatin formation IDA
IDA: Inferred from direct assay
33980486 GOA
Cellular Component GO Annotation Evidence References Source
is active in nucleus IDA
IDA: Inferred from direct assay
33980486 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SAMD1 Protein Structure

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (355 - 411)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 432 a.a.
Protein Preferred Names Protein Names

sterile alpha motif domain-containing protein 1

  • SAM domain containing 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12421 SAMD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22793 Samd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29306 Samd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SAMD1 RGD RGD:7529921
Mus musculus SAMD1 MGD MGI:2142433
Others SAMD1 NCBI