1. Gene
  2. SLC28A2 - solute carrier family 28 member 2 Gene

SLC28A2 - solute carrier family 28 member 2 Gene

Homo sapiens

Also known as CNT2; HCNT2; SPNT1; HsT17153

Gene ID: 9153 | Gene type: protein coding

About SLC28A2

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:45,252,234-45,277,846 (from NCBI)

This gene has 4 transcripts (splice variants), 198 orthologues and 2 paralogues. Biased expression in small intestine (RPKM 43.4), duodenum (RPKM 31.3) and 4 other tissues.

Summary

Enables neurotransmitter transmembrane transporter activity and nucleoside transmembrane transporter activity. Involved in several processes, including nucleoside transport; purine nucleobase transmembrane transport; and pyrimidine-containing compound transmembrane transport. Predicted to be located in membrane. Predicted to be part of brush border membrane; coated vesicle; and vesicle membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC28A2 Products(1)

mRNA Protein Name
NM_004212.4 NP_004203.2 sodium/nucleoside cotransporter 2

SLC28A2 Protein Structure

Nucleos_tra2_N

Nucleos_tra2_N: Na+ dependent nucleoside transporter N-terminus (179 - 251)

Gate

Gate: Nucleoside recognition (259 - 354)

Nucleos_tra2_C

Nucleos_tra2_C: Na+ dependent nucleoside transporter C-terminus (362 - 585)

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  • 658 a.a.
Protein Preferred Names Protein Names

sodium/nucleoside cotransporter 2

CNT 2

Related Diseases

Diseases Alias
Hyperuricemia

Blood Urate Raized

Uricacidemia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC28A2 VGNC VGNC:77445
Rattus norvegicus SLC28A2 RGD RGD:61840
Bos taurus SLC28A2 VGNC VGNC:34792