MEX3A - mex-3 RNA binding family member A Gene

Also Known as RKHD4; MEX-3A; RNF162

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 92312

About MEX3A

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,072,013-156,082,465 (from NCBI)

This gene has 2 transcripts (splice variants), 194 orthologues and 3 paralogues. Broad expression in endometrium (RPKM 3.0), ovary (RPKM 2.6) and 16 other tissues.

Summary

Enables RNA binding activity. Located in P-body and cytosol. [provided by Alliance of Genome Resources, Apr 2022]

MEX3A Products (1)

mRNA Protein Name
NM_001093725.2 NP_001087194.1 RNA-binding protein MEX3A

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
23408853 GOA
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
23408853 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEX3A Protein Structure

KH_1

KH_1: KH domain (134 - 193)

KH_1

KH_1: KH domain (225 - 284)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (468 - 509)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 520 a.a.
Protein Preferred Names Protein Names

RNA-binding protein MEX3A

  • RING finger and KH domain-containing protein 4

Related Diseases

Diseases Alias
Robinow Syndrome, Autosomal Dominant 1

  • Autosomal Dominant Robinow Syndrome 1

  • DRS1

  • Robinow Dwarfism

  • Fetal Face Syndrome

  • Acral Dysostosis With Facial And Genital Abnormalities

  • Robinow, Autosomal Dominant Syndrome, Type 1
Malignant Breast Melanoma

  • Malignant Melanoma Of Breast

  • Breast Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08372 MEX3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22636 Mex3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29151 Mex3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MEX3A VGNC VGNC:107896
Macaca mulatta MEX3A VGNC VGNC:106407
Bos taurus MEX3A VGNC VGNC:31419
Rattus norvegicus MEX3A RGD RGD:1564904
Mus musculus MEX3A MGD MGI:1919890
Others MEX3A NCBI