IP6K1 - inositol hexakisphosphate kinase 1 Gene

Homo sapiens

Also known as PiUS; IHPK1

Gene ID: 9807 | Gene type: protein coding

About IP6K1

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,724,294-49,786,542 (from NCBI)

This gene has 9 transcripts (splice variants), 218 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 17.4), testis (RPKM 16.8) and 25 other tissues.

Summary

This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

IP6K1 Products(3)

mRNA	Protein	Name
NM_001006115.3	NP_001006115.1	inositol hexakisphosphate kinase 1 isoform 2
NM_001242829.2	NP_001229758.1	inositol hexakisphosphate kinase 1 isoform 1
NM_153273.4	NP_695005.1	inositol hexakisphosphate kinase 1 isoform 1

IP6K1 Protein Structure

IPK

0
100
200
300
400
441 a.a.

Protein Preferred Names

Protein Names

inositol hexakisphosphate kinase 1

ATP:1D-myo-inositol-hexakisphosphate phosphotransferase

Recombinant IP6K1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77427	IP6K1/IHPK1 Protein, Human (sf9, His-GST)	Q92551 (M1-Q441)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-110079	TNP	Inhibitor	99.29%	Unkown
HY-150607	UNC7467		98.07%	Unkown
HY-122706	TBK1/IKKε-IN-3		/	Unkown
HY-153530	LI-2242		/	Unkown
HY-RS06861	IP6K1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	IP6K1	VGNC	VGNC:30237
Rattus norvegicus	IP6K1	RGD	RGD:71025
Felis catus	IP6K1	VGNC	VGNC:62951
Macaca mulatta	IP6K1	VGNC	VGNC:73621
Canis familiaris	IP6K1	VGNC	VGNC:42061
Mus musculus	IP6K1	MGD	MGI:1351633
Others	IP6K1	NCBI

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