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Cat. No.: HY-12432AR

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Gilteritinib hemifumarate (Standard)

(Synonyms: ASP2215 hemifumarate (Standard))

Gilteritinib hemifumarate (Standard) is the analytical standard of Gilteritinib hemifumarate. This product is intended for research and analytical applications. Gilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 1254053-84-3
Formula: C₂₉H₄₄N₈O₃ 0.5C₄H₄O₄
Molecular Weight:610.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Gilteritinib hemifumarate (Standard) Chemical Structure

CAS No.: 1254053-84-3

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1254053-84-3
Molecular Weight 610.75
Formula C₂₉H₄₄N₈O₃ 0.5C₄H₄O₄
SMILES

OC(/C=C/C(O)=O)=O.NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O
Synonyms

ASP2215 hemifumarate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. ASP2215, a novel FLT3/AXL inhibitor: Preclinical evaluation in acute myeloid leukemia (AML). 2014 ASCO Annual Meeting.

[2]. Mori M, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017 Oct;35(5):556-565. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Gilteritinib hemifumarate (Standard)

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Gilteritinib hemifumarate (Standard)

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Gilteritinib hemifumarate (Standard) Related Classifications

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