Glucocorticoid receptor modulator 3
Glucocorticoid receptor modulator 3 (Payload 6) is a thioester-containing glucocorticoid receptor modulator (IC50=0.6 nM). Glucocorticoid receptor modulator 3 is designed to inactivate unconjugated payloads rapidly through liver metabolism, thereby minimizing systemic exposure. Glucocorticoid receptor modulator 3 can be utilized in the development of antibody-drug conjugates (ADCs) targeting autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 2688785-13-7
- Formula: C29H32F3NO5S
- Molecular Weight:563.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2688785-13-7
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Molecular Weight 563.63
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Formula C29H32F3NO5S
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SMILES
O=C([C@@]1(OC(C2=CC(N)=C(C=C2)F)=O)[C@@H](C[C@@]3([C@]1(C)C[C@H](O)[C@]4(F)[C@@]5(C)C=CC(C=C5CC[C@]43[H])=O)[H])C)SCF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)