Gold(III) chloride trihydrate
Based on 1 publication(s) in Google Scholar
Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 16961-25-4
- Formula: HAuCl4.3H2O
- Molecular Weight:393.83
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Gold(III) chloride trihydrate
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Biological Activity
Gold nanoparticle synthesis method[1]:
1. Prepare a 2.5 mM HAuCl4·3H2O solution by mixing 0.05 g of Gold(III) chloride trihydrate with 50 mL of deionized water.
2. Prepare a 6.6 mM sodium hydroxide (NaOH) solution by mixing 0.0264 g of NaOH with 100 mL of deionized water.
3. Control the pH of 10 mL of HAuCl4·3H2O solution by adding NaOH until the pH reaches 6.6. This process heats the solution to 85 °C for 30 minutes under vigorous stirring.
4. Prepare a 5 mM sodium citrate (C6H5Na3O7) solution by mixing 0.073 g of sodium citrate with 50 mL of deionized water.
5. Heat 10 mL of sodium citrate solution to about 85°C for about 20 minutes and add HAuCl4·3H2O solution after vigorous stirring to obtain a deep red gold nanoparticle solution.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16961-25-4
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Appearance Solid
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Molecular Weight 393.83
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Formula HAuCl4.3H2O
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Color Yellow to orange
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SMILES
[H+].[Cl-][Au+3]([Cl-])([Cl-])[Cl-].O
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Synonyms
Chloroauric acid trihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Metabolism-Driven Colorimetric "Read-to-Answer" Sensor Array for Bacterial Discrimination and Antimicrobial Susceptibility Testing. [Abstract]2025 Aug 12;97(31):17040-17049. PMID: 40737437
Solvent & Solubility
H2O : ≥ 200 mg/mL (507.83 mM)
DMSO : 100 mg/mL (253.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (12.70 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (12.70 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (923 KB)
- English - EN (923 KB)
- Français - FR (923 KB)
- Deutsch - DE (923 KB)
- Norwegian - NO (923 KB)
- Español - ES (923 KB)
- Swedish - SV (923 KB)
- Italian - IT (923 KB)
- Korean - KR (923 KB)
- Portuguese - PT (923 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.5392 mL | 12.6958 mL | 25.3917 mL | 63.4792 mL |
| 5 mM | 0.5078 mL | 2.5392 mL | 5.0783 mL | 12.6958 mL | |
| 10 mM | 0.2539 mL | 1.2696 mL | 2.5392 mL | 6.3479 mL | |
| 15 mM | 0.1693 mL | 0.8464 mL | 1.6928 mL | 4.2319 mL | |
| 20 mM | 0.1270 mL | 0.6348 mL | 1.2696 mL | 3.1740 mL | |
| 25 mM | 0.1016 mL | 0.5078 mL | 1.0157 mL | 2.5392 mL | |
| 30 mM | 0.0846 mL | 0.4232 mL | 0.8464 mL | 2.1160 mL | |
| 40 mM | 0.0635 mL | 0.3174 mL | 0.6348 mL | 1.5870 mL | |
| 50 mM | 0.0508 mL | 0.2539 mL | 0.5078 mL | 1.2696 mL | |
| 60 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0580 mL | |
| 80 mM | 0.0317 mL | 0.1587 mL | 0.3174 mL | 0.7935 mL | |
| 100 mM | 0.0254 mL | 0.1270 mL | 0.2539 mL | 0.6348 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Gold(III) chloride trihydrate Related Classifications
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