1. Metabolic Enzyme/Protease
    Neuronal Signaling
    GPCR/G Protein
  2. Phospholipase
    Dopamine Receptor
  3. Halopemide

Halopemide 

Cat. No.: HY-119093 Purity: >99.0%
Handling Instructions

Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent.

For research use only. We do not sell to patients.

Halopemide Chemical Structure

Halopemide Chemical Structure

CAS No. : 59831-65-1

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 504 In-stock
Estimated Time of Arrival: December 31
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg USD 925 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All Phospholipase Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent[1][2].

IC50 & Target[1][2]

PLD1

220 nM (IC50)

PLD2

310 nM (IC50)

dopamine receptors

 

In Vitro

Halopemide (1-2 μM; 21 day) affects calcification in transdifferentiated MOVAS cells[3].

In Vivo

Halopemide (10 mg/kg; p.o.) induces dyskinesias in the majority of monkeys tested[2].

Molecular Weight

416.88

Formula

C₂₁H₂₂ClFN₄O₂

CAS No.

59831-65-1

SMILES

O=C(C1=CC=C(C=C1)F)NCCN2CCC(CC2)N3C4=CC=C(C=C4NC3=O)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

HalopemidePhospholipaseDopamine ReceptorpsychotropiccalcificationdyskinesiascancerMOVAScellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Halopemide
Cat. No.:
HY-119093
Quantity:
MCE Japan Authorized Agent: