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HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells.

For research use only. We do not sell to patients.

HDAC-IN-55 Chemical Structure

HDAC-IN-55 Chemical Structure

CAS No. : 1268674-16-3

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5 mg USD 450 In-stock
10 mg USD 750 In-stock
25 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

HDAC-IN-55 Related Antibodies

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Description

HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells[1].

In Vitro

HDAC-IN-55(8j) acts on SW620 cell line and H520 cell line with the EC50 values of 4.47 and 1.61 μM, respectively[1].
HDAC-IN-55(8j) (10 μM, 24 h) can increase the expression of E-cadherin in SW620 cells and inhibit the proliferation of SW620 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HDAC-IN-55 Related Antibodies
Molecular Weight

311.34

Formula

C17H17N3O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=NOC(C2=CC=CO2)=C1)NCCCCC3=CC=NC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (321.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2119 mL 16.0596 mL 32.1192 mL
5 mM 0.6424 mL 3.2119 mL 6.4238 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2119 mL 16.0596 mL 32.1192 mL 80.2981 mL
5 mM 0.6424 mL 3.2119 mL 6.4238 mL 16.0596 mL
10 mM 0.3212 mL 1.6060 mL 3.2119 mL 8.0298 mL
15 mM 0.2141 mL 1.0706 mL 2.1413 mL 5.3532 mL
20 mM 0.1606 mL 0.8030 mL 1.6060 mL 4.0149 mL
25 mM 0.1285 mL 0.6424 mL 1.2848 mL 3.2119 mL
30 mM 0.1071 mL 0.5353 mL 1.0706 mL 2.6766 mL
40 mM 0.0803 mL 0.4015 mL 0.8030 mL 2.0075 mL
50 mM 0.0642 mL 0.3212 mL 0.6424 mL 1.6060 mL
60 mM 0.0535 mL 0.2677 mL 0.5353 mL 1.3383 mL
80 mM 0.0401 mL 0.2007 mL 0.4015 mL 1.0037 mL
100 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.8030 mL
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HDAC-IN-55 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC-IN-551268674-16-3OthersE-cadherincancerInhibitorinhibitorinhibit

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HDAC-IN-55
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HY-153607
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