Head activator neuropeptide
Based on 1 Customer Validation
Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 79943-68-3
- Formula: C54H84N12O14
- Molecular Weight:1125.32
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
GPR37[1]
Head activator neuropeptide (2 nM, 0-60 min) stimulates internalisation of GPR37 in COS-7 cell transfected with GPR37-FLAG[1].
Head activator neuropeptide (EC50: 3.3 nM) increases in Ca2+ mobilisation in CHO-K1 cells transfected with apoaequorin and GPR37[1].
Head activator neuropeptide (EC50: 5.6 nM) stimulates a current increase in frog oocytes expressing GPR37[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79943-68-3
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Appearance Solid
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Molecular Weight 1125.32
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Formula C54H84N12O14
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Color White to off-white
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Sequence Shortening
Glp-PPGGSKVILF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (88.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8886 mL | 4.4432 mL | 8.8864 mL | 22.2159 mL |
| 5 mM | 0.1777 mL | 0.8886 mL | 1.7773 mL | 4.4432 mL | |
| 10 mM | 0.0889 mL | 0.4443 mL | 0.8886 mL | 2.2216 mL | |
| 15 mM | 0.0592 mL | 0.2962 mL | 0.5924 mL | 1.4811 mL | |
| 20 mM | 0.0444 mL | 0.2222 mL | 0.4443 mL | 1.1108 mL | |
| 25 mM | 0.0355 mL | 0.1777 mL | 0.3555 mL | 0.8886 mL | |
| 30 mM | 0.0296 mL | 0.1481 mL | 0.2962 mL | 0.7405 mL | |
| 40 mM | 0.0222 mL | 0.1111 mL | 0.2222 mL | 0.5554 mL | |
| 50 mM | 0.0178 mL | 0.0889 mL | 0.1777 mL | 0.4443 mL | |
| 60 mM | 0.0148 mL | 0.0741 mL | 0.1481 mL | 0.3703 mL | |
| 80 mM | 0.0111 mL | 0.0555 mL | 0.1111 mL | 0.2777 mL |