hENT4-IN-1
Based on 1 Customer Validation
hENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 949467-71-4
- Formula: C26H48N8O2
- Molecular Weight:504.71
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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Heterocyclic Compound Library
HY-L138
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 949467-71-4
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Appearance Solid
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Molecular Weight 504.71
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Formula C26H48N8O2
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Color Light yellow to yellow
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SMILES
CC(C)CN(C1=NC(NCCO)=NC2=C1N=C(NCCO)N=C2N(CC(C)C)CC(C)C)CC(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 125 mg/mL (247.67 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang C, et al. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochem Pharmacol. 2013 Dec 1;86(11):1531-40. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9813 mL | 9.9067 mL | 19.8134 mL | 49.5334 mL |
| 5 mM | 0.3963 mL | 1.9813 mL | 3.9627 mL | 9.9067 mL | |
| 10 mM | 0.1981 mL | 0.9907 mL | 1.9813 mL | 4.9533 mL | |
| 15 mM | 0.1321 mL | 0.6604 mL | 1.3209 mL | 3.3022 mL | |
| 20 mM | 0.0991 mL | 0.4953 mL | 0.9907 mL | 2.4767 mL | |
| 25 mM | 0.0793 mL | 0.3963 mL | 0.7925 mL | 1.9813 mL | |
| 30 mM | 0.0660 mL | 0.3302 mL | 0.6604 mL | 1.6511 mL | |
| 40 mM | 0.0495 mL | 0.2477 mL | 0.4953 mL | 1.2383 mL | |
| 50 mM | 0.0396 mL | 0.1981 mL | 0.3963 mL | 0.9907 mL | |
| 60 mM | 0.0330 mL | 0.1651 mL | 0.3302 mL | 0.8256 mL | |
| 80 mM | 0.0248 mL | 0.1238 mL | 0.2477 mL | 0.6192 mL | |
| 100 mM | 0.0198 mL | 0.0991 mL | 0.1981 mL | 0.4953 mL |
hENT4-IN-1 Related Classifications
HY-110165 Related Classifications
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