2. Membrane Transporter/Ion Channel
  3. Monoamine Transporter
  4. hENT4-IN-1

hENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM.

For research use only. We do not sell to patients.

hENT4-IN-1 Chemical Structure

hENT4-IN-1 Chemical Structure

CAS No. : 949467-71-4

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

hENT4-IN-1 Related Antibodies

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Description

hENT4-IN-1 is a potent and selective human ENT4 (equilibrative nucleoside transporter 4) inhibitor with an IC50 of 74.4 nM[1].

Molecular Weight

504.71

Formula

C26H48N8O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(C)CN(C1=NC(NCCO)=NC2=C1N=C(NCCO)N=C2N(CC(C)C)CC(C)C)CC(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (247.67 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9813 mL 9.9067 mL 19.8134 mL
5 mM 0.3963 mL 1.9813 mL 3.9627 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9813 mL 9.9067 mL 19.8134 mL 49.5334 mL
5 mM 0.3963 mL 1.9813 mL 3.9627 mL 9.9067 mL
10 mM 0.1981 mL 0.9907 mL 1.9813 mL 4.9533 mL
15 mM 0.1321 mL 0.6604 mL 1.3209 mL 3.3022 mL
20 mM 0.0991 mL 0.4953 mL 0.9907 mL 2.4767 mL
25 mM 0.0793 mL 0.3963 mL 0.7925 mL 1.9813 mL
30 mM 0.0660 mL 0.3302 mL 0.6604 mL 1.6511 mL
40 mM 0.0495 mL 0.2477 mL 0.4953 mL 1.2383 mL
50 mM 0.0396 mL 0.1981 mL 0.3963 mL 0.9907 mL
60 mM 0.0330 mL 0.1651 mL 0.3302 mL 0.8256 mL
80 mM 0.0248 mL 0.1238 mL 0.2477 mL 0.6192 mL
100 mM 0.0198 mL 0.0991 mL 0.1981 mL 0.4953 mL
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hENT4-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hENT4-IN-1949467-71-4Monoamine TransporterInhibitorinhibitorinhibit

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