DA 1686
DA 1686 is an orally active naphthalene derivative that induces bradycardia and mild hypotension. DA 1686 can be used in the study of arrhythmias.
For research use only. We do not sell to patients.
- CAS No.: 13071-27-7
- Formula: C23H32N2O2
- Molecular Weight:368.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DA 1686 reduces aconitine-induced tachycardia and responsiveness to increased electrical stimulation in isolated guinea-pig auricles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
DA 1686 (20 mg/kg; i.v.; slow infusion) protects anaesthetized dogs from Adrenaline (HY-B0447)-induced death during benzol inhalation[1].
DA 1686 protects rats from arrhythmia induced by intravenous administration of 34 μg/kg Aconitine[1].
DA 1686 delays the onset of Ouabain (HY-B1457)-induced arrhythmia, ventricular fibrillation, and cardiac arrest in guinea-pigs[1].
DA 1686 reduces tachycardia induced by 10 days of daily 0.2 mg Thyroxine (HY-18341) administration in rabbits[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Dog[1]
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Dosage:20 mg/kg
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Administration:i.v.; slow infusion
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Result:Protected anaesthetized dogs from death induced by rapid intravenous adrenaline administration during benzol inhalation.
Chemical Information
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CAS No. 13071-27-7
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Molecular Weight 368.51
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Formula C23H32N2O2
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SMILES
N1(CCC(CCN2CCOCC2)C3=CC=CC4=C3C=CC=C4)CCOCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DA 1686 Related Classifications
HY-120730 Related Classifications
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