HX1
Based on 1 Customer Validation
HX1 is a potent reversible myeloperoxidase (MPO) inhibitor with an IC50 value of 50 nM. HX1 is bound within the active site cavity above the heme and blocks the substrate channel. HX1 is promising for research of inflammatory diseases.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 1520083-61-7
- Formula: C14H10F6N4O3
- Molecular Weight:396.24
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1520083-61-7
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Appearance Solid
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Molecular Weight 396.24
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Formula C14H10F6N4O3
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Color White to off-white
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SMILES
O=C(C1=CN=C(NCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)NC1=O)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (252.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5237 mL | 12.6186 mL | 25.2372 mL | 63.0931 mL |
| 5 mM | 0.5047 mL | 2.5237 mL | 5.0474 mL | 12.6186 mL | |
| 10 mM | 0.2524 mL | 1.2619 mL | 2.5237 mL | 6.3093 mL | |
| 15 mM | 0.1682 mL | 0.8412 mL | 1.6825 mL | 4.2062 mL | |
| 20 mM | 0.1262 mL | 0.6309 mL | 1.2619 mL | 3.1547 mL | |
| 25 mM | 0.1009 mL | 0.5047 mL | 1.0095 mL | 2.5237 mL | |
| 30 mM | 0.0841 mL | 0.4206 mL | 0.8412 mL | 2.1031 mL | |
| 40 mM | 0.0631 mL | 0.3155 mL | 0.6309 mL | 1.5773 mL | |
| 50 mM | 0.0505 mL | 0.2524 mL | 0.5047 mL | 1.2619 mL | |
| 60 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0516 mL | |
| 80 mM | 0.0315 mL | 0.1577 mL | 0.3155 mL | 0.7887 mL | |
| 100 mM | 0.0252 mL | 0.1262 mL | 0.2524 mL | 0.6309 mL |
HX1 Related Classifications
HY-116188 Related Classifications
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