hsa-miR-126-5p antagomir
hsa-miR-126-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Molecular Weight:7061.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 7061.65
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
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miRBase Accession Number
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Mature miRNA Sequence
CAUUAUUACUUUUGGUACGCG
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Stem-loop ID
hsa-mir-126
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Stem-loop Sequence
CGCUGGCGACGGGACAUUAUUACUUUUGGUACGCGCUGUGACACUUCAAACUCGUACCGUGAGUAAUAAUGCGCCGUCCACGGCA
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Species
Human, Mouse, Rat, Alligator mississippiensis, Anolis carolinensis, Astatotilapia burtoni, Bovine, Chicken, Chrysemys picta, Cyprinus carpio, Dog, Gadus morhua, Horse, Ictalurus punctatus, Metriaclima zebra, Microcebus murinus, Monodelphis domestica, Neolamprologus brichardi, Nomascus leucogenys, Oreochromis niloticus, Ornithorhynchus anatinus, Oryzias latipes, Pig, Pundamilia nyererei, Python bivittatus, Salmo salar, Xenopus laevis, Xenopus tropicalis, Zebrafish
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)