HSD17B13-IN-21
HSD17B13-IN-21 (compound 17) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM and? < 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-21? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis).
For research use only. We do not sell to patients.
- CAS No.: 2758802-18-3
- Formula: C21H18Cl2N2O4S
- Molecular Weight:465.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 17β-HSD Isoforms
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Biological Activity
Chemical Information
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CAS No. 2758802-18-3
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Molecular Weight 465.35
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Formula C21H18Cl2N2O4S
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SMILES
O=C(C1=CC(Cl)=C(O)C=C1)NC2=C(C(NCCC3=C(OC)C=CC=C3)=O)SC(Cl)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)