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Cat. No.: HY-180163

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HSP70-IN-8

HSP70-IN-8 (Compound 1b) is a HSP70 inhibitor and Alpinetin (HY-N0625A) derivative. HSP70-IN-8 inhibits the expression of HSP70 protein.HSP70-IN-8 exhibits excellent anti-liver cancer activity.

For research use only. We do not sell to patients.

Formula: C₂₁H₁₇NO₆S₂
Molecular Weight:443.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HSP70-IN-8 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HSP70-IN-8 (Compound 1b) is a HSP70 inhibitor and Alpinetin (HY-N0625A) derivative. HSP70-IN-8 inhibits the expression of HSP70 protein.HSP70-IN-8 exhibits excellent anti-liver cancer activity^[1].

IC₅₀ & Target^[1]

HSP70

All HSP Isoforms :

Chemical Information

Molecular Weight 443.49
Formula C₂₁H₁₇NO₆S₂
SMILES

COC1=C(C(CC(C2=CC=CC=C2)O3)=O)C3=CC(OC(CN4C(CSC4=S)=O)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yi Y, et al. Design, synthesis, and activity evaluation of alpinetin derivatives as potential anti-liver cancer drugs. Bioorg Med Chem Lett. 2026 Mar;132:130482. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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HSP70-IN-8

All HSP Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HSP70-IN-8 Related Classifications

HY-180163 Related Classifications