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Cat. No.: HY-N13088

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Hyperidione D

Hyperidione D is apotent antidepressant agent. Hyperidione D shows neuroprotective effects.

For research use only. We do not sell to patients.

Formula: C₃₅H₅₄O₇
Molecular Weight:586.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Hyperidione D Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Hyperidione D is apotent antidepressant agent. Hyperidione D shows neuroprotective effects^[1].

In Vitro

Hyperidione D (10 µM) shows neuroprotective effects against corticosterone (HY-B1618)-induced damage in SH-SY5Y cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Hyperidione D (1.25, 2.5, and 5 mg/kg; i.p.) shows antidepressant activity in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

20 g, adult male C57BL/6J mice^[1]
Dosage:

1.25, 2.5, and 5 mg/kg
Administration:

I.p.; 1 h before the test
Result:

Showed antidepressant activity and significant reducted in CORT levels.

Chemical Information

Molecular Weight 586.80
Formula C₃₅H₅₄O₇
SMILES

CC(C)(O)[C@H](O1)CC2=C1[C@]3(C/C=C(C)\C)C([C@@](C(C(C)C)=O)([C@](CC/C=C(C)/C)(C)[C@H](C[C@@H](O)C(C)(O)C)C3)C2=O)=O
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pan XG, et al. New polycyclic polyprenylated acylphloroglucinols with antidepressant activities from Hypericum perforatum L. Bioorg Chem. 2024 Jul 16;151:107657. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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