BIO-11006
BIO-11006 is a peptide that inhibits the function of the MARCKS protein. BIO-11006 attenuates LPS-induced neutrophil influx into the lungs, NF-κB activation, and expression of the proinflammatory cytokines KC and TNF-α. BIO-11006 also reverses disease progression in an LPS-induced mouse lung injury model. BIO-11006 is indicated for research on acute lung injury/acute respiratory distress syndrome (ALI/ARDS).
For research use only. We do not sell to patients.
- CAS No.: 901117-03-1
- Formula: C46H75N13O15
- Molecular Weight:1050.17
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) BIO-11006
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Biological Activity
Chemical Information
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CAS No. 901117-03-1
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Molecular Weight 1050.17
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Formula C46H75N13O15
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SMILES
CC(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@H](C(O)=O)CCCCN)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Mol Biol Rep
MARCKS N-terminal sequence-derived inhibitor peptides impair monocytic ROS production and migration via MARCKS-independent effects. [Abstract]2025 Sep 17;52(1):911. PMID: 40960646
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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