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Cat. No.: HY-107751

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BW373U86

Name: BW373U86
Brand: MedChemExpress
SKU: HY-107751
Availability: PreOrder

(Synonyms: SNC86)

BW373U86 (SNC86) is a δ-opioid receptor agonist with an IC₅₀ of 1.49 nM. BW373U86 shows antidepressant-like effects.

For research use only. We do not sell to patients.

CAS No.: 155836-50-3
Formula: C₂₇H₃₇N₃O₂
Molecular Weight:435.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BW373U86 Chemical Structure

CAS No.: 155836-50-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BW373U86 (SNC86) is a δ-opioid receptor agonist with an IC₅₀ of 1.49 nM. BW373U86 shows antidepressant-like effects^[1].

IC₅₀ & Target

IC₅₀: 1.49 nM (δ-opioid receptor)^[1]

All Opioid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	0.4 nM Compound: 21, BW-373U86	Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS binding Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS binding	[PMID: 18788723]

Chemical Information

CAS No. 155836-50-3
Molecular Weight 435.60
Formula C₂₇H₃₇N₃O₂
SMILES

C[C@@H](CN([C@@H](C1)C)CC=C)N1[C@H](C2=CC=C(C=C2)C(N(CC)CC)=O)C3=CC(O)=CC=C3
Synonyms

SNC86
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jutkiewicz EM, et al. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. J Pharmacol Exp Ther. 2004 Apr;309(1):173-81. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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