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Cat. No.: HY-N19134

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Shearinine B

(Synonyms: (+)-Shearinine B)

Shearinine B ((+)-Shearinine B) is an indole-diterpenoid alkaloid that can be found in the marine-derived fungus Penicillium janthinellum Biourge and Eupenicillium shearii. Shearinine B causes mortality in fall armyworm Spodoptera frugiperda and reduces growth rate of Helicoverpa zea larvae.

For research use only. We do not sell to patients.

CAS No.: 163136-25-2
Formula: C₃₇H₄₇NO₅
Molecular Weight:585.79

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Shearinine B Chemical Structure

CAS No.: 163136-25-2

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Shearinine B (100 ppm) causes a 94% reduction in growth rate of Helicoverpa zea larvae^[2].

Shearinine B (100 ppm) causes a 50% reduction in feeding rate of Carpophilus hemipterus larvae^[2].
Shearinine B (50 μg per 75-mg cotton leaf disk; topical application to leaf disk) causes 84% mortality and 85% reduction in leaf damage in Spodoptera frugiperda larvae^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 163136-25-2
Molecular Weight 585.79
Formula C₃₇H₄₇NO₅
SMILES

C[C@]12C3=C(C[C@@]1(CC[C@]4(O)[C@]2(C)CC[C@]5(C4=CC(=O)[C@@H]([C@](C)(C)O)O5)[H])[H])C=6C(N3)=CC7=C(C6)C[C@]8(C7=CC(C)(C)OC8(C)C)[H]
Synonyms

(+)-Shearinine B
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Microorganisms
Eupenicillium shearii
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Smetanina OF, et al. Indole alkaloids produced by a marine fungus isolate of Penicillium janthinellum Biourge. J Nat Prod. 2007 Jun;70(6):906-9. [Content Brief]

[2]. Gilbert N. Belofsky, et al. Antiinsectan alkaloids: Shearinines A-C and a new paxilline derivative from the ascostromata of Eupenicillium shearii. Tetrahedron Vol. 51, No. 14, pp. 3959-3968, 1995.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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