IDH1 Inhibitor 3
IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H.
For research use only. We do not sell to patients.
- CAS No.: 2171081-24-4
- Formula: C31H25F4N5O3
- Molecular Weight:591.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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IDH-305IDH1(R132) Inhibitor
Biological Activity
Description
IC50 & Target
IC50: 45 nM (IDH1R132H)[1].
Chemical Information
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CAS No. 2171081-24-4
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Molecular Weight 591.56
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Formula C31H25F4N5O3
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SMILES
O=C([C@@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@]3(C(NC4CC(F)(F)C4)=O)CCC5=C3C=CC=C5)C6=CC(F)=CC(F)=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDH1 Inhibitor 3 Related Classifications
HY-107977 Related Classifications
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