IKZF2-degrader 4
IKZF2-degrader 4 (Page 650, third compound from the top in the right column) is an IKZF2 Molecular glue degrader. IKZF2-degrader 4 degrades IKZF2 protein. IKZF2-degrader 4 can be used in the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2989880-79-5
- Formula: C32H39N3O3
- Molecular Weight:513.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IKZF2 |
In Vitro
IKZF2 (IKAROS family zinc finger 2), also known as Helios, is a member of the Ikaros zinc finger protein family. It is a transcription factor specifically highly expressed in regulatory T cells (Tregs), crucial for maintaining Treg function and stability, thereby suppressing anti-tumor immune responses.
Molecular glue degraders are small molecules that induce novel protein-protein interactions between target proteins and E3 ubiquitin ligases. They trigger ubiquitination and proteasome degradation of target proteins by forming ternary complexes.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2989880-79-5
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Molecular Weight 513.67
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Formula C32H39N3O3
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SMILES
O=C1C2=CC=C(C[C@@H]3[C@H](CCCC3)NC4CCC(C5=CC=CC=C5)CC4)C=C2CN1C6C(NC(CC6)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IKZF2-degrader 4 Related Classifications
HY-185300 Related Classifications
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