ARN19689
ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions.
For research use only. We do not sell to patients.
- CAS No.: 2320521-34-2
- Formula: C19H27N5O4S
- Molecular Weight:421.51
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 42 nM (N Acylethanolamine-Hydrolyzing Acid Amidase)[1]
ARN19689 (30 μM) inhibits the activity of human FAAH and human acid ceramidase by 25 and 34%, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2320521-34-2
-
Molecular Weight 421.51
-
Formula C19H27N5O4S
-
SMILES
O=S(N1[C@@H]2C[C@H](C[C@H]1CC2)OC3=NC=C(COCC)N=C3)(C4=C(C)NN=C4C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)