CB30900
CB30900 is an inhibitor for thymidylate synthase with an IC50 of 0.2 μM. CB30900 exhibits cytotoxicity in W1L2 with an IC50 of 0.13 μM.
For research use only. We do not sell to patients.
- CAS No.: 145788-82-5
- Formula: C31H32FN5O9
- Molecular Weight:637.61
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 145788-82-5
-
Molecular Weight 637.61
-
Formula C31H32FN5O9
-
SMILES
O=C1C2=CC(CN(C3=CC(F)=C(C=C3)C(N[C@H](C(O)=O)CCC(N[C@@H](C(O)=O)CCC(O)=O)=O)=O)CC#C)=C(C)C=C2NC(C)=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Walton MI, et al., Preclinical pharmacology of CB30900, a novel dipeptide inhibitor of thymidylate synthase, in mice. J Pharmacol Exp Ther. 1996 May;277(2):909-16. [Content Brief]
[2]. Aherne GW, et al., Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cells. Biochem Pharmacol. 1996 May 17;51(10):1293-301 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB30900 Related Classifications
HY-120293 Related Classifications
Powered by Bioz