Ebiratide
Ebiratide (HOE-427 free base) is an ACTH 4-9 derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy. Ebiratide enhances acetycholine (ACh) metabolism in rat brain.
For research use only. We do not sell to patients.
- CAS No.: 105611-68-5
- Formula: C48H73N11O10S
- Molecular Weight:996.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electoconvulsive shock induced and Scopolamine (HY-N0296)-induced memory impairment in NMRI mice[1]
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Dosage:0.1-30 μg/kg
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Administration:s.c., single dose
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Result:Reduced the retention latency.
Chemical Information
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CAS No. 105611-68-5
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Molecular Weight 996.23
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Formula C48H73N11O10S
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Synonyms
HOE-427 free base
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Sequence
{Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2}
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Sequence Shortening
{Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9(3):575-81. [Content Brief]
[2]. G Wiemer, et al. Neurochemical effects of the synthetic ACTH4-9-analog Hoe 427 (Ebiratide) in rat brain. Peptides. 1988 Sep-Oct;9(5):1081-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ebiratide Related Classifications
HY-19648 Related Classifications
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