Ebiratide TFA
Based on 1 Customer Validation
Ebiratide (HOE-427) TFA is an ACTH 4-9 derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy. Ebiratide TFA enhances acetycholine (ACh) metabolism in rat brain.
For research use only. We do not sell to patients.
- Purity: 99.04%
- Formula: C48H73N11O10S.xC2HF3O2
- Molecular Weight:996.23 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electoconvulsive shock induced and Scopolamine (HY-N0296)-induced memory impairment in NMRI mice[1]
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Dosage:0.1-30 μg/kg
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Administration:s.c., single dose
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Result:Reduced the retention latency.
Chemical Information
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Appearance Solid
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Molecular Weight 996.23 (free base)
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Formula C48H73N11O10S.xC2HF3O2
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Color White to off-white
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Synonyms
HOE-427 TFA
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Sequence
{Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2}
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Sequence Shortening
{Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9(3):575-81. [Content Brief]
[2]. G Wiemer, et al. Neurochemical effects of the synthetic ACTH4-9-analog Hoe 427 (Ebiratide) in rat brain. Peptides. 1988 Sep-Oct;9(5):1081-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)