Ebiratide
Ebiratide (HOE-427 free base) is an ACTH 4-9 derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy. Ebiratide enhances acetycholine (ACh) metabolism in rat brain.
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- CAS 番号: 105611-68-5
- 分子式: C48H73N11O10S
- 分子量:996.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electoconvulsive shock induced and Scopolamine (HY-N0296)-induced memory impairment in NMRI mice[1]
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Dosage:0.1-30 μg/kg
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Administration:s.c., single dose
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Result:Reduced the retention latency.
化学情報
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CAS 番号 105611-68-5
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分子量 996.23
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分子式 C48H73N11O10S
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別名
HOE-427 free base
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配列
{Met(O2)}-Glu-His-Phe-{d-Lys}-{Phe-NH(CH2)8NH2}
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シーケンスの短縮
{Met(O2)}-EHF-{d-Lys}-{Phe-NH(CH2)8NH2}
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9(3):575-81. [Content Brief]
[2]. G Wiemer, et al. Neurochemical effects of the synthetic ACTH4-9-analog Hoe 427 (Ebiratide) in rat brain. Peptides. 1988 Sep-Oct;9(5):1081-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ebiratide 関連分類
HY-19648 関連分類
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