iNOs-IN-5
iNOs-IN-5 (Compound BN-4) is an inhibitor for iNOS with an IC50 of 0.1707 μM, and reduces NO levels in LPS (HT-D1056)-induced RAW264.7 cells. iNOs-IN-5 reduces the hypoxic injury stimulated ROS and lactate dehydrogenase expression, and exhibits anti-necrosis and anti-apoptosis efficacy. iNOs-IN-5 exhibits anti-cerebral ischemia and neuroprotective activities in SD rat models. iNOs-IN-5 is blood-brain barrier penetrable.
For research use only. We do not sell to patients.
- CAS No.: 3067565-40-3
- Formula: C22H27N3O2
- Molecular Weight:365.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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iNOS 0.1707 μM (IC50) |
Chemical Information
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CAS No. 3067565-40-3
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Molecular Weight 365.47
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Formula C22H27N3O2
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SMILES
O=C(OC1CCCC)C2=C1C=CC(NCC3=CC(CNC(C)=N)=CC=C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
iNOs-IN-5 Related Classifications
HY-168096 Related Classifications
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