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Cat. No.: HY-160654

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IRAK4 modulator-1

Name: IRAK4 modulator-1
Brand: MedChemExpress
SKU: HY-160654
Price: 65.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

IRAK4 modulator-1 (example 161) is a modulator of IRAK4 with IC₅₀=4.647 μM. IRAK4 modulator-1 can be used to study IRAK-mediated disorders.

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Pureté : 99.11%
CAS No.: 1356014-97-5
Formule: C₁₉H₁₃ClN₄O₂
Masse moléculaire:364.79

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

IRAK4 modulator-1 Chemical Structure

CAS No.: 1356014-97-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Protocole (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IRAK4 modulator-1 (example 161) is a modulator of IRAK4 with IC₅₀=4.647 μM. IRAK4 modulator-1 can be used to study IRAK-mediated disorders^[1].

IC₅₀ & Target

IRAK4

4.647 μM (IC₅₀, ^[1])

Voir tous les produits spécifiques à Isoform IRAK :

Chemical Information

CAS No. 1356014-97-5
Appearance Solid
Masse moléculaire 364.79
Formule C₁₉H₁₃ClN₄O₂
Color White to off-white
SMILES

O=C(C1=C2N=CC=CN2N=C1)NC3=CC(Cl)=CC=C3OC4=CC=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (278 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Pyrazolo[1,5-a]pyrimidine and thieno[3,2-b]pyrimidine derivatives as IRAK4 modulators and their preparation. World Intellectual Property Organization, et al. World Intellectual Property Organization, WO2012007375 A1. 2012-01-19.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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