Iron(II) sulfate heptahydrate, for cell culture, 99%
Based on 2 publication(s) in Google Scholar
Iron(II) sulfate heptahydrate, for cell culture, 99% (Ferrous sulfate heptahydrate, for cell culture, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, for cell culture, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, for cell culture, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, for cell culture, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer.
For research use only. We do not sell to patients.
- Purity : 99.90%
- CAS No.: 7782-63-0
- Formula: FeSO4.7H2O
- Molecular Weight:278.01
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Iron(II) sulfate heptahydrate, 99%Iron Salt -
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Publications Citing Use of MedChemExpress (MCE) Iron(II) sulfate heptahydrate, for cell culture, 99%
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Biological Activity
Description
In Vitro
Iron (II) sulfate (16-125 μM; 48 h) heptahydrate, for cell culture, 99% inhibits the growth of K562 chronic myeloid leukemia cells and T47D breast cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
Iron(II) sulfate (0.4 mg/kg b.w./10 days; p.o., via drinking water; 10 days) heptahydrate, for cell culture, 99% is less effective than iron oxide nanoparticles in treating iron deficiency anemia in rats[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male albino rats with iron deficiency anemia model induced by a standard iron-free basal diet for six weeks[3]
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Dosage:0.4 mg/kg b.w./10 days
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Administration:Administered in the drinking water, 10 days
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Result:Increased red blood cells count, hemoglobin concentration, hematocrit value, serum ferritin, transferrin saturation, and serum iron levels.
Caused a significant increase in serum malondialdehyde and C-reactive protein levels, indicating more oxidative stress and inflammation.
Chemical Information
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CAS No. 7782-63-0
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Appearance Solid
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Molecular Weight 278.01
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Formula FeSO4.7H2O
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Color Blue to blue-green
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SMILES
[FeSO4·7H2O]
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Synonyms
Ferrous sulfate heptahydrate, for cell culture, 99%
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Metab
Gut microbiota-derived isovaleric acid alleviates atrial fibrillation by suppressing GSDME-dependent pyroptosis. [Abstract]2026 Feb 3;38(2):370-387.e10. PMID: 41638192 -
Curr Eye Res
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe2+ Production. [Abstract]2023 Jan;48(1):25-33. PMID: 36300537
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (359.70 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Kok SH, et al. Paradoxical proliferative potential of iron (II) sulphate on cancer cells after the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. Int J Mol Med. 2007 Jun;19(6):971-5. [Content Brief]
[2]. Appel MJ, et al. Disposition, accumulation and toxicity of iron fed as iron (II) sulfate or as sodium iron EDTA in rats. Food Chem Toxicol. 2001 Mar;39(3):261-9. doi: 10.1016/s0278-6915(00)00137-x. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.5970 mL | 17.9850 mL | 35.9699 mL | 89.9248 mL |
| 5 mM | 0.7194 mL | 3.5970 mL | 7.1940 mL | 17.9850 mL | |
| 10 mM | 0.3597 mL | 1.7985 mL | 3.5970 mL | 8.9925 mL | |
| 15 mM | 0.2398 mL | 1.1990 mL | 2.3980 mL | 5.9950 mL | |
| 20 mM | 0.1798 mL | 0.8992 mL | 1.7985 mL | 4.4962 mL | |
| 25 mM | 0.1439 mL | 0.7194 mL | 1.4388 mL | 3.5970 mL | |
| 30 mM | 0.1199 mL | 0.5995 mL | 1.1990 mL | 2.9975 mL | |
| 40 mM | 0.0899 mL | 0.4496 mL | 0.8992 mL | 2.2481 mL | |
| 50 mM | 0.0719 mL | 0.3597 mL | 0.7194 mL | 1.7985 mL | |
| 60 mM | 0.0599 mL | 0.2997 mL | 0.5995 mL | 1.4987 mL | |
| 80 mM | 0.0450 mL | 0.2248 mL | 0.4496 mL | 1.1241 mL | |
| 100 mM | 0.0360 mL | 0.1798 mL | 0.3597 mL | 0.8992 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Iron(II) sulfate heptahydrate, for cell culture, 99% Related Classifications
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