Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside
Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside is an anti-inflammatory agent isolated from barley (Hordeum vulgare L.) leaves.
For research use only. We do not sell to patients.
- CAS No.: 1016970-92-5
- Formula: C43H48O23
- Molecular Weight:932.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside Chemical Structure](https://file.medchemexpress.com/product_pic/hy-n13038.gif "Click to View Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside Chemical Structure")
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1016970-92-5
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Molecular Weight 932.83
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Formula C43H48O23
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SMILES
OC1=C2C(OC(C3=CC=C(C=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=CC2=O)=CC(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)COC(/C=C/C6=CC(OC)=C(C=C6)O)=O)=C1[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside Related Classifications
HY-N13038 Related Classifications
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