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Cat. No.: HY-178358

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JAX-44

JAX-44 is a potent root architecture modulator. JAX-44 maintains primary root length while substantially increasing lateral root numbers, thereby optimizing the plant’s overall root system. JAX-44 is the metabolic precursor of JAX-77 (HY-178359) and can be converted to Indole-3-butyric acid (IBA) (HY-N0186). JAX-44 can be used for auxin biology and root development research.

For research use only. We do not sell to patients.

CAS No.: 2352652-76-5
Formula: C₁₄H₁₇NO₃
Molecular Weight:247.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

JAX-44 Chemical Structure

CAS No.: 2352652-76-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

In Vitro

JAX-44 (0-30 μM, 4 days) shows potent promoting effects on lateral root formation (LRF) by inducing and advancing the formation of lateral root primordia (LRP) in Arabidopsis thaliana^[1].
JAX-44 (0-100 μM, 5 days) promotes adventitious root formation in rice (Oryza sativa cv. Haenuki), while inhibiting primary root elongation at concentrations above 3 μM^[1].
JAX-44 enables the selective inhibition of LRF in Arabidopsis thaliana through its conversion to N- or O-methylated derivatives^[1].
JAX-44 (100 μM, 3 h) is rapidly hydrolyzed to JAX-77 and subsequently converted to IBA in Arabidopsis thaliana^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2352652-76-5
Molecular Weight 247.29
Formula C₁₄H₁₇NO₃
SMILES

O=C(OC)C(O)CCCC1=CNC2=C1C=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kikuchi R, et al. Indole-3-Butyric Acid (IBA) Derivatives for Root Architecture Modulation: Potent Promoters via In Vivo Conversion to IBA and Selective Inhibitors for Lateral Root Formation. ACS Omega. 2025 Sep 21;10(38):44717-44727. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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