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Cat. No.: HY-170868

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CL2A-FL118

CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118.

For research use only. We do not sell to patients.

CAS No.: 3025194-00-4
Formula: C₇₂H₉₃N₁₁O₂₃
Molecular Weight:1480.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CL2A-FL118 Chemical Structure

CAS No.: 3025194-00-4

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One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

Description

CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 3025194-00-4
Molecular Weight 1480.57
Formula C₇₂H₉₃N₁₁O₂₃
SMILES

O=C(OCC1=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O)=O)C=C1)O[C@](C5=C(CO6)C(N7CC8=CC9=CC%10=C(OCO%10)C=C9N=C8C7=C5)=O)(CC)C6=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mathi GR, et al. Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy. Bioorg Med Chem Lett. 2025 Apr 1;118:130085. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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CL2A-FL118

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CL2A-FL118 Related Classifications

HY-170868 Related Classifications