ICG-azide
Based on 1 Customer Validation
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction.
For research use only. We do not sell to patients.
- Purity: 99.66%
- Formula: C48H56N6O4S
- Molecular Weight:813.06
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 813.06
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Formula C48H56N6O4S
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Color Dark purple to black
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SMILES
CC(C1=C(N/2CCCCCC(NCCCN=[N+]=[N-])=O)C=CC3=CC=CC=C31)(C)C2=C/C=C/C=C/C=C/C4=[N+](CCCCS(=O)([O-])=O)C(C=CC5=C6C=CC=C5)=C6C4(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (30.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Amirshaghaghi A, et, al. Site-Specific Labeling of Cyanine and Porphyrin Dye-Stabilized Nanoemulsions with Affibodies for Cellular Targeting. J Am Chem Soc. 2018 Oct 24;140(42):13550-13553. [Content Brief]
[2]. Singh S, et, al. Size-tunable ICG-based contrast agent platform for targeted near-infrared photoacoustic imaging. Photoacoustics. 2022 Dec 11:29:100437. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2299 mL | 6.1496 mL | 12.2992 mL | 30.7480 mL |
| 5 mM | 0.2460 mL | 1.2299 mL | 2.4598 mL | 6.1496 mL | |
| 10 mM | 0.1230 mL | 0.6150 mL | 1.2299 mL | 3.0748 mL | |
| 15 mM | 0.0820 mL | 0.4100 mL | 0.8199 mL | 2.0499 mL | |
| 20 mM | 0.0615 mL | 0.3075 mL | 0.6150 mL | 1.5374 mL | |
| 25 mM | 0.0492 mL | 0.2460 mL | 0.4920 mL | 1.2299 mL | |
| 30 mM | 0.0410 mL | 0.2050 mL | 0.4100 mL | 1.0249 mL |