LM-030
LM-030 (BPR277), cyclic depsipeptide, is a potent kallikrein-related peptidase 7 (KLK7) and human neutrophil elastase inhibitor with IC50 values of 1 and 10 nM. LM-030 can be used for the study of Netherton syndrome.
For research use only. We do not sell to patients.
- CAS No.: 1122484-55-2
- Formula: C46H72N8O12
- Molecular Weight:929.11
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
KLK7 1 nM (IC50) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 1122484-55-2
-
Molecular Weight 929.11
-
Formula C46H72N8O12
-
Synonyms
BPR277
-
Sequence
Gln-lactone[Thr-Leu-{Oaa}-Tyr-Ile]
-
Sequence Shortening
Q-lactone[TL-{Oaa}-YI]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)