Mal-PEG2-NH2
Mal-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Mal-PEG2-NH2 TFA) that retains the same biological activity.
For research use only. We do not sell to patients.
- CAS No.: 660843-22-1
- Formula: C10H16N2O4
- Molecular Weight:228.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 660843-22-1
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Molecular Weight 228.25
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Formula C10H16N2O4
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SMILES
O=C(C=C1)N(CCOCCOCCN)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)