20-Hydroxyganoderic Acid G
20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS.
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- CAS 番号: 400604-12-8
- 分子式: C30H44O9
- 分子量:548.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
21.33 μM
Compound: 27
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay
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[PMID: 27335254] |
化学情報
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CAS 番号 400604-12-8
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分子量 548.66
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分子式 C30H44O9
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SMILES
CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4([C@H](O)C3=O)C)[C@@](C)(O)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H]
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
20-Hydroxyganoderic Acid G 関連分類
HY-N7018 関連分類
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