93-O17S
Based on 1 Customer Validation
93-O17S is an ionizable lipid. 93-O17S is involved in the construction of LNP. 93-O17S can achieve mRNA delivery to the spleen.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 2227008-67-3
- 分子式: C44H83N3O4S2
- 分子量:782.28
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体内実験
化学情報
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CAS 番号 2227008-67-3
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性状 Oil
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分子量 782.28
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分子式 C44H83N3O4S2
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Color Light yellow to yellow
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SMILES
O=C(CCN(CCCN1C=NC=C1)CCC(OCCSCCCCCCCCCCCCCC)=O)OCCSCCCCCCCCCCCCCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (127.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 100 mg/mL (127.83 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Omo-Lamai S, et al. Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects. bioRxiv [Preprint]. 2024 Apr 18:2024.04.16.589801. [Content Brief]
[2]. Delehedde C, et al. Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles. Pharmaceutics. 2021 Jun 24;13(7):945. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.2783 mL | 6.3916 mL | 12.7831 mL | 31.9579 mL |
| 5 mM | 0.2557 mL | 1.2783 mL | 2.5566 mL | 6.3916 mL | |
| 10 mM | 0.1278 mL | 0.6392 mL | 1.2783 mL | 3.1958 mL | |
| 15 mM | 0.0852 mL | 0.4261 mL | 0.8522 mL | 2.1305 mL | |
| 20 mM | 0.0639 mL | 0.3196 mL | 0.6392 mL | 1.5979 mL | |
| 25 mM | 0.0511 mL | 0.2557 mL | 0.5113 mL | 1.2783 mL | |
| 30 mM | 0.0426 mL | 0.2131 mL | 0.4261 mL | 1.0653 mL | |
| 40 mM | 0.0320 mL | 0.1598 mL | 0.3196 mL | 0.7989 mL | |
| 50 mM | 0.0256 mL | 0.1278 mL | 0.2557 mL | 0.6392 mL | |
| 60 mM | 0.0213 mL | 0.1065 mL | 0.2131 mL | 0.5326 mL | |
| 80 mM | 0.0160 mL | 0.0799 mL | 0.1598 mL | 0.3995 mL | |
| 100 mM | 0.0128 mL | 0.0639 mL | 0.1278 mL | 0.3196 mL |
93-O17S 関連分類
HY-153372 関連分類
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