Lagociclovir
Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV.
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- CAS 番号: 92562-88-4
- 分子式: C10H12FN5O3
- 分子量:269.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
HBV[1]
Lagociclovir (FLG) (6 days) shows inhibitory activity with IC50s of 8 ± 3.8, 9 ± 2.5, 13 ± 3.4 and 15 ± 6.8 μM against 3TC-R HBV, wt HBV, PMEA-R HBV and 3TC+PMEA-R HBV, respectively in transiently transfected Huh7 cells[1].
Lagociclovir (0-100 μM; 6 days) inhibits the replication of wild-type and drug-resistant mutants of HBV in transiently transfected Huh7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 92562-88-4
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分子量 269.23
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分子式 C10H12FN5O3
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SMILES
O=C(N=C(N)N1)C2=C1N([C@@H]3O[C@H](CO)[C@@H](F)C3)C=N2
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別名
MIV-210
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)