Timonacic
Based on 2 publication(s) in Google Scholar
Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 444-27-9
- 分子式: C4H7NO2S
- 分子量:133.17
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Timonacic
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生物活性
Timonacic can form a chelate with palladium(II) chloride in a buffered medium. Based on this, a spectrophotometric method has been developed to effectively determine its content. This method exhibits a good linear relationship, high precision, and accuracy, and is suitable for pharmaceutical quality control[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 444-27-9
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性状 Solid
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分子量 133.17
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分子式 C4H7NO2S
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Color White to off-white
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SMILES
O=C(C1NCSC1)O
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別名
1,3-Thiazolidine-4-carboxylic acid
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
H2O : 14.29 mg/mL (107.31 mM; ultrasonic and warming and heat to 60°C)
DMSO : 6 mg/mL (45.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bakry RS, et al. Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications. J Pharm Biomed Anal. 1998 May;17(1):95-101. [Content Brief]
[2]. H U Weber, et al. Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine. Arch Gerontol Geriatr. 1982 Dec;1(4):299-310. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 7.5092 mL | 37.5460 mL | 75.0920 mL | 187.7300 mL |
| 5 mM | 1.5018 mL | 7.5092 mL | 15.0184 mL | 37.5460 mL | |
| 10 mM | 0.7509 mL | 3.7546 mL | 7.5092 mL | 18.7730 mL | |
| 15 mM | 0.5006 mL | 2.5031 mL | 5.0061 mL | 12.5153 mL | |
| 20 mM | 0.3755 mL | 1.8773 mL | 3.7546 mL | 9.3865 mL | |
| 25 mM | 0.3004 mL | 1.5018 mL | 3.0037 mL | 7.5092 mL | |
| 30 mM | 0.2503 mL | 1.2515 mL | 2.5031 mL | 6.2577 mL | |
| 40 mM | 0.1877 mL | 0.9386 mL | 1.8773 mL | 4.6932 mL | |
| H2O | 50 mM | 0.1502 mL | 0.7509 mL | 1.5018 mL | 3.7546 mL |
| 60 mM | 0.1252 mL | 0.6258 mL | 1.2515 mL | 3.1288 mL | |
| 80 mM | 0.0939 mL | 0.4693 mL | 0.9386 mL | 2.3466 mL | |
| 100 mM | 0.0751 mL | 0.3755 mL | 0.7509 mL | 1.8773 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Timonacic 関連分類
HY-B1169 関連分類
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