Aciculatin
Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 134044-97-6
- 分子式: C22H22O8
- 分子量:414.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
2.65 μM
Compound: aciculatin
|
Cytotoxicity against human CEM cells after 48 hrs by alamar blue assay
Cytotoxicity against human CEM cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| HT-29 | IC50 |
25.98 μM
Compound: aciculatin
|
Cytotoxicity against human HT-29 cells after 48 hrs by alamar blue assay
Cytotoxicity against human HT-29 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| MCF7 | IC50 |
3.16 μM
Compound: aciculatin
|
Cytotoxicity against human MCF7 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MCF7 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| NCI-H460 | IC50 |
46.94 μM
Compound: aciculatin
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by alamar blue assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
化学情報
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CAS 番号 134044-97-6
-
分子量 414.41
-
分子式 C22H22O8
-
SMILES
COC1=CC(O)=C(C(C=C(C2=CC=C(C=C2)O)O3)=O)C3=C1[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)