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Alloc-Val-Ala-OH

(別名: ((Allyloxy)carbonyl)-L-valyl-L-alanine)
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Alloc-Val-Ala-OH (((Allyloxy)carbonyl)-L-valyl-L-alanine) is a building block in the synthesis of Tesirine, a clinical antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.

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  • CAS 番号: 330970-70-2
  • 分子式: C12H20N2O5
  • 分子量:272.30
  • 保管条件:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Alloc-Val-Ala-OH Chemical Structure
    Alloc-Val-Ala-OH 構造式
CAS 番号: 330970-70-2
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  • Alloc-Val-Ala-OH Chemical Structure
    Alloc-Val-Ala-OH Chemical Structure
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  • Alloc-Val-Ala-OH