Amogammadex
Amogammadex (Adamgammadex; Aom0498) is a modified γ-cyclodextrin (HY-W040040) derivative and neuromuscular blocking agent. Amogammadex forms inactive, tight inclusion complexes with free Rocuronium (HY-17033) and Vecuronium (HY-B0118A), and reverses the neuromuscular blockade induced by them in a concentration-dependent manner. Amogammadex can be used in research related to neuromuscular blockade reversal.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1309580-40-2
- 分子式: C88H136N8O56S8
- 分子量:2458.56
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 1309580-40-2
-
分子量 2458.56
-
分子式 C88H136N8O56S8
-
SMILES
CC(N[C@@](C(O)=O)([H])CSC[C@@H]1[C@@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H](O3)[C@H](O)[C@@H](O)[C@H](O[C@@H](O4)[C@H](O)[C@@H](O)[C@H](O[C@@H](O5)[C@H](O)[C@@H](O)[C@H](O[C@@H](O6)[C@H](O)[C@@H](O)[C@H]7[C@H]6CSC[C@@](C(O)=O)(NC(C)=O)[H])[C@H]5CSC[C@@](C(O)=O)(NC(C)=O)[H])[C@H]4CSC[C@]([H])(NC(C)=O)C(O)=O)[C@H]3CSC[C@@](NC(C)=O)([H])C(O)=O)[C@H](O2)CSC[C@](C(O)=O)([H])NC(C)=O)[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H](O[C@H]9[C@H](O)[C@@H](O)[C@@H](O7)O[C@@H]9CSC[C@](NC(C)=O)(C(O)=O)[H])O[C@@H]8CSC[C@@]([H])(C(O)=O)NC(C)=O)O1)=O
-
別名
Adamgammadex; Aom0498
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Qi, et al. 6-deoxy-6-thioether-amino acid cyclodextrin derivatives and preparation method thereof. WO2012068981A1. [Content Brief]
[2].
Zhao Y, et al. Efficacy and safety of adamgammadex for reversing rocuronium-induced deep neuromuscular block: a multicentre, randomised, double-blind, positive-controlled phase III trial. Br J Anaesth. 2025 Aug;135(2):331-339.
[Content Brief]
[3]. Stäuble CG, Blobner M. The future of neuromuscular blocking agents. Curr Opin Anaesthesiol. 2020 Aug;33(4):490-498. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Amogammadex 関連分類
HY-159818 関連分類
Powered by Bioz