Biotin-PEG2-OH
Based on 1 publication(s) in Google Scholar
Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 717119-80-7
- 分子式: C14H25N3O4S
- 分子量:331.43
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 Biotin-PEG2-OH
MorePROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 717119-80-7
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性状 Solid
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分子量 331.43
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分子式 C14H25N3O4S
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Color White to off-white
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SMILES
O=C(NCCOCCO)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Redox Biol
Overexpression of NUDT16L1 sustains proper function of mitochondria and leads to ferroptosis insensitivity in colorectal cancer. [Abstract]2024 Nov:77:103358. PMID: 39317106
溶剤 & 溶解度
DMSO : 100 mg/mL (301.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0172 mL | 15.0861 mL | 30.1723 mL | 75.4307 mL |
| 5 mM | 0.6034 mL | 3.0172 mL | 6.0345 mL | 15.0861 mL | |
| 10 mM | 0.3017 mL | 1.5086 mL | 3.0172 mL | 7.5431 mL | |
| 15 mM | 0.2011 mL | 1.0057 mL | 2.0115 mL | 5.0287 mL | |
| 20 mM | 0.1509 mL | 0.7543 mL | 1.5086 mL | 3.7715 mL | |
| 25 mM | 0.1207 mL | 0.6034 mL | 1.2069 mL | 3.0172 mL | |
| 30 mM | 0.1006 mL | 0.5029 mL | 1.0057 mL | 2.5144 mL | |
| 40 mM | 0.0754 mL | 0.3772 mL | 0.7543 mL | 1.8858 mL | |
| 50 mM | 0.0603 mL | 0.3017 mL | 0.6034 mL | 1.5086 mL | |
| 60 mM | 0.0503 mL | 0.2514 mL | 0.5029 mL | 1.2572 mL | |
| 80 mM | 0.0377 mL | 0.1886 mL | 0.3772 mL | 0.9429 mL | |
| 100 mM | 0.0302 mL | 0.1509 mL | 0.3017 mL | 0.7543 mL |