CID15997213
CID15997213 is a blood-brain barrier penetrating antiviral agent. CID15997213 targets the amino-terminal domain of the VEEV nonstructural protein 2 (nsP2). CID15997213 shows alphavirus-specific antiviral effect, inhibiting VEEV and Western equine encephalitis virus.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 900134-28-3
- 分子式: C21H22FN5O3
- 分子量:411.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero 76 | CC50 |
>50 μM
Compound: 1
|
Cytotoxicity against african green monkey Vero 76 cells after 3 days by Celltiter-Glo reagent based assay
Cytotoxicity against african green monkey Vero 76 cells after 3 days by Celltiter-Glo reagent based assay
|
[PMID: 25244572] |
| Vero 76 | EC50 |
0.3 μM
Compound: 1
|
Antiviral activity against Venezuelan equine encephalitis virus V3526 infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
Antiviral activity against Venezuelan equine encephalitis virus V3526 infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
|
[PMID: 25244572] |
| Vero 76 | EC50 |
0.6 μM
Compound: 1
|
Antiviral activity against Venezuelan equine encephalitis virus TrD infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
Antiviral activity against Venezuelan equine encephalitis virus TrD infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
|
[PMID: 25244572] |
| Vero 76 | EC50 |
0.8 μM
Compound: 1
|
Antiviral activity against Venezuelan equine encephalitis virus TC83 infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
Antiviral activity against Venezuelan equine encephalitis virus TC83 infected in Vero 76 cells assessed as reduction in virus-induced cytopathic effect after 2 days by Celltiter-Glo reagent based assay
|
[PMID: 25244572] |
化学情報
-
CAS 番号 900134-28-3
-
分子量 411.43
-
分子式 C21H22FN5O3
-
SMILES
O=C1C2=C(N=C(CN3CCN(CC3)CC)N1C4=C(F)C=CC=C4)C=CC([N+]([O-])=O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)