Coixenolide
Based on 1 Customer Validation
Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.93%
- CAS 番号: 29066-43-1
- 分子式: C38H70O4
- 分子量:590.96
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Coixenolide (0-1 %, 7 d) enhances the mycelial growth and polysaccharide production[2].
Coixenolide (0-0.25 %, 1-9 d) results in a quicker decrease in the glucose concentration of culture compared to the control[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 29066-43-1
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性状 Oil
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分子量 590.96
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分子式 C38H70O4
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Color Colorless to light yellow
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SMILES
CCCCCC/C=C\CCCCCCCC(O[C@H](C)[C@H](C)OC(CCCCCCCCC/C=C/CCCCCC)=O)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
Ethanol : ≥ 100 mg/mL (169.22 mM)
THF : 40 mg/mL (67.69 mM; Need ultrasonic)
DMSO : 2 mg/mL (3.38 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hu AJ, et al., Ultrasound assisted supercritical fluid extraction of oil and coixenolide from adlay seed. Ultrason Sonochem. 2007 Feb;14(2):219-24. [Content Brief]
[2]. Zhou, H., et al., (2014). Improved polysaccharide production in submerged culture of Ganoderma lucidum by the addition of coixenolide. Applied biochemistry and biotechnology, 172(3), 1497–1505. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / THF / Ethanol | 1 mM | 1.6922 mL | 8.4608 mL | 16.9216 mL | 42.3040 mL |
| THF / Ethanol | 5 mM | 0.3384 mL | 1.6922 mL | 3.3843 mL | 8.4608 mL |
| 10 mM | 0.1692 mL | 0.8461 mL | 1.6922 mL | 4.2304 mL | |
| 15 mM | 0.1128 mL | 0.5641 mL | 1.1281 mL | 2.8203 mL | |
| 20 mM | 0.0846 mL | 0.4230 mL | 0.8461 mL | 2.1152 mL | |
| 25 mM | 0.0677 mL | 0.3384 mL | 0.6769 mL | 1.6922 mL | |
| 30 mM | 0.0564 mL | 0.2820 mL | 0.5641 mL | 1.4101 mL | |
| 40 mM | 0.0423 mL | 0.2115 mL | 0.4230 mL | 1.0576 mL | |
| 50 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8461 mL | |
| 60 mM | 0.0282 mL | 0.1410 mL | 0.2820 mL | 0.7051 mL | |
| Ethanol | 80 mM | 0.0212 mL | 0.1058 mL | 0.2115 mL | 0.5288 mL |
| 100 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4230 mL |