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United States

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製品番号: HY-N15595

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Curvulol

Curvulol is an antimicrobial agent with a polyketide structure. Curvulol can be isolated from Taxus baccata ( Chaetosphaeronema achilleae). Curvulol has a significant cytotoxicity against L929 and KB-3-1 cells, and strongly inhibits Staphylococcus aureus biofilm formation with a MIC of 64 μg/mL.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 15817-76-2
分子式: C₁₀H₁₂O₄
分子量:196.20

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Curvulol 構造式

CAS 番号: 15817-76-2

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Curvulol (Compound 7) shows an antimicrobial activity against Rhodoturula glutinis DSM 10134, Schizosaccharomyces pombe DSM 70572, Staphylococcus aureus DSM 346 and Bacillus subtilis DSM 10 with a MIC of 33.33 μg/mL^[1].
Curvulol has a significant cytotoxicity with _IC50 s of 5.5 and 7.5  μg/mL for L929 and KB-3-1 cells, respectively^[1].
Curvulol (4-256 μg/mL) strongly inhibits Staphylococcus aureus biofilm formation of 96.18% at 256 μg/mL, and with a MIC of 64 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 15817-76-2
分子量 196.20
分子式 C₁₀H₁₂O₄
SMILES

OC1=C2C(CO[C@H]2C)=CC(OC)=C1O
Structure Classification
- Others
Initial Source
- Microorganisms
Chaetosphaeronema achilleae
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Narmani A, Teponno RB, Helaly SE, Arzanlou M, Stadler M. Cytotoxic, anti-biofilm and antimicrobial polyketides from the plant associated fungus Chaetosphaeronema achilleae. Fitoterapia. 2019 Nov; 139:104390. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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濃度濃度

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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