Cyclo(-Met-Pro)
Based on 1 Customer Validation
Cyclo(-Met-Pro) is a cyclic dipeptide consisting of the amino acids methionine and proline. Cyclo(-Met-Pro) exhibits weak inhibitory activity against the influenza A virus (H3N2) (5 mM, 2.1% inhibition), while cis-cyclo(Leu-Pro) and cis-cyclo(Phe-Pro) shows significant antiviral activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.80%
- CAS 番号: 53049-06-2
- 分子式: C10H16N2O2S
- 分子量:228.31
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
化学情報
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CAS 番号 53049-06-2
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性状 Solid
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分子量 228.31
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分子式 C10H16N2O2S
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Color White to off-white
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配列
Cyclo(Met-Pro)
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シーケンスの短縮
Cyclo(MP)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (438.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
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データシート (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3800 mL | 21.9000 mL | 43.8001 mL | 109.5002 mL |
| 5 mM | 0.8760 mL | 4.3800 mL | 8.7600 mL | 21.9000 mL | |
| 10 mM | 0.4380 mL | 2.1900 mL | 4.3800 mL | 10.9500 mL | |
| 15 mM | 0.2920 mL | 1.4600 mL | 2.9200 mL | 7.3000 mL | |
| 20 mM | 0.2190 mL | 1.0950 mL | 2.1900 mL | 5.4750 mL | |
| 25 mM | 0.1752 mL | 0.8760 mL | 1.7520 mL | 4.3800 mL | |
| 30 mM | 0.1460 mL | 0.7300 mL | 1.4600 mL | 3.6500 mL | |
| 40 mM | 0.1095 mL | 0.5475 mL | 1.0950 mL | 2.7375 mL | |
| 50 mM | 0.0876 mL | 0.4380 mL | 0.8760 mL | 2.1900 mL | |
| 60 mM | 0.0730 mL | 0.3650 mL | 0.7300 mL | 1.8250 mL | |
| 80 mM | 0.0548 mL | 0.2738 mL | 0.5475 mL | 1.3688 mL | |
| 100 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0950 mL |